Boron Neutron Capture Therapy: A New Generation of Targeted Charged-Particle Radiotherapy

Boron Neutron Capture Therapy

A project aimed at the development of an accelerator facility devoted to Boron Neutron Capture Therapy (BNCT) is ongoing at the National Atomic Energy Commission of Argentina [1]. In a first stage of development, the accelerator will be capable of delivering proton or deuteron beams of 30 mA at about 1.4 MeV which is suitable for neutron production through the 9Be(d,n) reaction. In this context...

A Monte Carlo study of SPECT in boron neutron capture therapy for a heterogeneous human phantom

Background: Boron neutron capture therapy (BNCT) is a binary radiotherapy combining biochemical targeting with neutron irradiation. However, monitoring the boron distribution is a fundamental problem in BNCT. Prompt gamma rays emitted by boron capture reaction can be used to address the issue. Materials and Methods: The general-purpose Monte Carlo toolkits Geant4 and MCNP were used for the simu...

شبیه سازی چشمه 7li(p,n)7be جهت استفاده در bnct (boron neutron capture therapy)

با توجه به اینکه امروزه بیماران بسیاری در سراسر جهان از سرطان رنج میبرند،دانشمندان در تلاشند روشهای درمانی جدیدتر و بهتری را کشف کنند .یکی از این روشها "درمان بوسیله گیراندازی نوترون توسط بور (bnct)" نام دارد که میتواند یکی از بهترین روشهای مفید و موثر و جایگزین در درمان سرطانهایی از نوع glioblastoma و melanoma نسبت به روشهای متداولی چون شیمی درمانی یا رادیوتراپی باشد.در این روش هدف انجام واکنش...

Boron Neutron Capture Therapy: A Biochemical Perspective

Boron Neutron Capture Therapy of Cancer1

brain tumors. Shortly thereafter, a clinical trial was initiated at the Brookhaven National Laboratory in cooperation with Sweet and others at the Massachusetts General Hospital utilizing borax as the capture agent (5, 6). The objective at that time was to use BNCT as an adjunct to surgery for the treatment of patients with the most highly malignant and therapeutically refractory of all brain t...